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​​Adaptations in Alimentary Canal Structure in Subjects with Zooanthroponotic Occult MetaBiomimetic Infectious Encephalitis

ABSTRACT

Postmortem examinations revealed significant alimentary canal differences in individuals testing negative and positive for Zooanthroponotic Occult MetaBiomimetic Infectious (ZOMBI) Encephalitis. On the tongue, benign migratory glossitis was documented in 1.1% of ZOMBI encephalitis- negative subjects and 43.9% of ZOMBI encephalitis-positive subjects. Semicircular extensions of submucosa resembling plicae circulares normally limited to the small intestine were found in the esophagus in 2.7% and stomach in 7.5% of ZOMBI encephalitis-negative subjects, but in the esophagus in 88.4% and stomach in 77.7% of ZOMBI encephalitis-positive subjects. Villi were the most numerous in the duodenum, jejunum, and ileum of ZOMBI encephalitis-negative subjects, where they were reduced in ZOMBI encephalitis-positive subjects but the most abundant in the esophagus and stomach. The stomach was longer and the jejunum, ileum, and caecum were shorter in ZOMBI encephalitis-positive subjects. ZOMBI encephalitis-positive subjects also exhibited inflammation of the lamina propria of the small intestine and greater capillary infiltration of the esophagus and stomach. The colon was empty in 47.9% of ZOMBI encephalitis-positive subjects and 35.2% of ZOMBI encephalitis-negative subjects. Increasing in magnitude with disease progression, these differences may reflect modifications in nutrient absorption related to dietary changes, decreased function in the small intestine, and/or alterations in digestive efficiency in ZOMBI encephalitis-positive individuals, and may be considered for inclusion in the diagnosis and staging of ZOMBI encephalitis.

KEY WORDS 
alimentary canal, benign migratory glossitis, lamina propria, plicae circulares, villi, virtual autopsy, ZOMBI encephalitis, zombie